Depot Hill State School prides itself on the hardworking, passionate and committed staff who continually strive to guide the students to achieve their full potential.
- Ms Elizabeth Jacobson - Principal, Year 5, 6
- Mr Ken Leslie - Principal, Year 5, 6
- Miss Jane Downing - Year Prep, 1
- Ms Louise Bidenko - Year 1, 2
- Miss Leisa Tennent - Year 3, 4
- Teacher Aides
- Mrs Colleen Portch
- Miss Wendy Young
- Miss Tori Harrison
- Ms Vicky Doyle
- Ms Nikki Welsh
- Mrs Belinda Johansen
- Mrs Tiara Dowdle
- Ms Kylie Dampier
- Lucinda Britton
- Dallas Upkett
- Ms Kerry Fehlhaber - Cleaner
- Mr Lex Janke - School's Officer
- Mrs Cindy Laidlaw - Administration Officer
- Miss Steph Ruddick - Head of Curriculum CQ Small School Cluster
- Mr Luke Miller - L.O.T.E.
- Miss Sarah McKean - Physical Education
- Mrs Ester Madsen - Religious Instruction
- Mr Jeffery Bookallil - I.T
- Ms Erin Clifford - Social Worker
- Ms Jovelyn Dig-O - Guidance Officer
- Mr Benjamin Araufo: Chaplin